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There are 7 fifteen-letter words containing 2D, 2E, 2I and M

ADENOIDECTOMIESadenoidectomies n. Plural of adenoidectomy.
ADENOIDECTOMY n. the surgical removal of the adenoids, also ADENECTOMY.
DIMENHYDRINATESdimenhydrinates n. Plural of dimenhydrinate.
DIMENHYDRINATE n. a crystalline antihistamine used esp. to prevent nausea, as in motion sickness.
DIPHENHYDRAMINEdiphenhydramine n. (Pharmacology) An antihistamine and anticholinergic drug that blocks the effect of histamine at H1 receptor…
DIPHENHYDRAMINE n. a type of antihistamine.
DISINTERMEDIATEdisintermediate v. (Business, banking, finance) To carry out disintermediation.
MALADMINISTEREDmaladministered v. Simple past tense and past participle of maladminister.
MALADMINISTER v. to administer wrongly.
MIDDELMANNETJIEmiddelmannetjie n. (South Africa) A ridge between ruts made by wheels in a dirt or gravel road.
MIDDELMANNETJIE n. (South African) a ridge between the ruts made by wheels in a dirt road.
MISGUIDEDNESSESmisguidednesses n. Plural of misguidedness.
MISGUIDEDNESS n. the state of being misguided.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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