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There are 9 fifteen-letter words containing 2D, 4E and T

DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DELIGHTEDNESSESDELIGHTEDNESS n. the state of being delighted.
FATHEADEDNESSESFATHEADEDNESS n. FATHEADED, stupid.
HOTHEADEDNESSESHOTHEADEDNESS n. HOTHEADED, rash, impetuous.
INTERDEPENDENCEinterdependence n. The condition of being interdependent.
INTERDEPENDENCE n. the state of being interdependent, also INTERDEPENDENCY.
INTERDEPENDENCYinterdependency n. A mutual dependence, connection or correlation.
INTERDEPENDENCY n. the state of being interdependent, also INTERDEPENDENCE.
INTERDEPENDENTSSorry, definition not available.
TENDERHEARTEDLYtenderheartedly adv. In a tenderhearted manner, with caring and compassion.
tender-heartedly adv. Alternative form of tenderheartedly.
TENDERHEARTED adv. easily moved to love, pity, or sorrow.
UNPRECEDENTEDLYunprecedentedly adv. In an unprecedented manner.
UNPRECEDENTED adv. having no precedent.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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