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There are 9 fourteen-letter words containing 2D, 2E, 2M and S

CHORDAMESODERMchordamesoderm n. (Anatomy) The axial mesoderm, which lies along the central axis under the neural tube and gives rise to the notochord.
CHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DECOMMISSIONEDdecommissioned v. Simple past tense and past participle of decommission.
DECOMMISSION v. to remove (as a ship or nuclear power plant) from service.
DISCOMMENDABLEdiscommendable adj. Deserving disapprobation or blame.
DISCOMMENDABLE adj. that can be discommended.
DISEMBODIMENTSdisembodiments n. Plural of disembodiment.
DISEMBODIMENT n. the state of being disembodied.
LAMPADEDROMIESLAMPADEDROMY n. a foot race with lighted torches, esp. a relay race in which the torch is passed on, also LAMPADEPHORIA.
MEDDLESOMENESSmeddlesomeness n. The qualities of being meddlesome; officiousness, intrusiveness.
MEDDLESOMENESS n. the state of being meddlesome.
MELODRAMATISEDmelodramatised v. Simple past tense and past participle of melodramatise.
MELODRAMATISE v. to make melodramatic, also MELODRAMATIZE.
SIMPLEMINDEDLYsimplemindedly adv. In a simpleminded manner.
simple-mindedly adv. In a simple-minded manner. Lacking sophistication or intelligence.
SIMPLEMINDED adv. devoid of subtlety.
SLEDGEHAMMEREDsledgehammered v. Simple past tense and past participle of sledgehammer.
SLEDGEHAMMER v. to strike with a sledgehammer.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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