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There are 10 ten-letter words containing D, 2E, M, N, P and U

EPIDENDRUMepidendrum n. (Botany) Any plant of the genus Epidendrum.
Epidendrum prop.n. A taxonomic genus within the family Orchidaceae – certain orchids.
EPIDENDRUM n. a genus of tropical plant, also EPIDENDRONE.
IMPRUDENCEimprudence n. (Uncountable) The quality or state of being imprudent; lack of prudence, caution, discretion or circumspection.
imprudence n. (Countable) An imprudent act.
IMPRUDENCE n. the state of being imprudent.
IMPUDENCESimpudences n. Plural of impudence.
IMPUDENCE n. shameless boldness, also IMPUDENCY.
SPODUMENESspodumenes n. Plural of spodumene.
SPODUMENE n. a monoclinic pyroxene, a silicate of aluminium and lithium occurring in granite pegmatites.
UNEMPLOYEDunemployed adj. Having no job despite being able and willing to work.
unemployed adj. Having no use, not doing work.
UNEMPLOYED adj. not employed.
UNEXAMPLEDunexampled adj. Lacking prior examples; unprecedented.
UNEXAMPLED adj. having no example or similar case; being without precedent.
UNHAMPEREDunhampered adj. Not hampered.
UNHAMPERED adj. not hampered.
UNPAMPEREDunpampered adj. Not pampered.
UNPAMPERED adj. not pampered.
UNPERFUMEDunperfumed adj. Not perfumed.
UNPERFUMED adj. not perfumed.
UNTEMPEREDuntempered adj. Not tempered; not conditioned by a process.
untempered adj. In the case of a person, inexperienced; untested.
UNTEMPER v. to destroy the temper of.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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