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There are 12 ten-letter words containing 2D, 2E, N, P and S

DEPENDANTSdependants n. Plural of dependant.
DEPENDANT n. a person who depends on another for support, also DEPENDENT.
DEPENDENTSdependents n. Plural of dependent.
DEPENDENT n. a person who depends on another for support.
DEPREHENDSdeprehends v. Third-person singular simple present indicative form of deprehend.
DEPREHEND v. (obsolete) to catch; to seize.
DESPONDENTdespondent adj. In low spirits from loss of hope or courage.
DESPONDENT adj. feeling or showing extreme discouragement.
DISPONDEESdispondees n. Plural of dispondee.
DISPONDEE n. a double spondee; a foot consisting of four long syllables.
DISPREDDENDISPREAD v. (Spenser) to spread out, also DISPRED.
PEDANTISEDpedantised v. Simple past tense and past participle of pedantise.
PEDANTISE v. to play the pedant, also PEDANTIZE.
PERDENDOSIperdendosi n. (Music) A gradual fading away.
PERDENDOSI adv. (Italian) slowing and softening at the same time, also PERDENDO.
PRESCINDEDprescinded v. Simple past tense and past participle of prescind.
PRESCIND v. to consider separately.
RESPLENDEDresplended v. Simple past tense and past participle of resplend.
RESPLEND v. to shine brilliantly.
SPLENDIDERsplendider adj. Comparative form of splendid: more splendid.
SPLENDID adj. magnificent.
UNDERSPENDunderspend v. To spend too little of the funds appropriated or allocated.
underspend n. An amount by which an allocated amount is not expended.
UNDERSPEND v. to spend less than.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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