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There are 4 ten-letter words containing 2D, 2E, M and 2S

DAMNEDESTSDAMNEDEST n. utmost effort, in phrase to do one's damnedest, also DAMNDEST, DAMNEST.
DERMESTIDSdermestids n. Plural of dermestid.
DERMESTID n. any of a family of beetles with clubbed antennae, destructive to organic material.
DISSEMBLEDdissembled v. Simple past tense and past participle of dissemble.
DISSEMBLE v. to hide true feelings, motives, or the facts.
MINDEDNESSmindedness n. The state of being minded in a particular way (as in narrow-mindedness, absent-mindedness).
MINDEDNESS n. an inclination to do something.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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