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There are 12 words containing D, 2E, 2P and X

APOPLEXEDapoplexed adj. (Obsolete) Affected with apoplexy.
APOPLEX v. to affect with apoplexy.
PERPLEXEDperplexed adj. Confused or puzzled.
perplexed adj. Bewildered.
perplexed v. Simple past tense and past participle of perplex.
APPENDIXESappendixes n. Plural of appendix.
APPENDIX n. something added on.
PREEXPOSEDpreexposed adj. Exposed (to light, chemicals etc) prior to another process.
PREEXPOSE v. to expose in advance.
PERPLEXEDLYperplexedly adv. In a confused or puzzled manner.
PERPLEXEDLY adv. PERPLEXED.
PREEXEMPTEDPREEXEMPT v. to exempt beforehand.
UNPERPLEXEDunperplexed adj. Not confused or puzzled.
UNPERPLEX v. to free from perplexity.
EXOPEPTIDASEexopeptidase n. (Biochemistry) Any of a group of enzymes which catalyze the removal of a single amino acid from the…
EXOPEPTIDASE n. any of a group of enzymes that hydrolyze peptide bonds.
EXPROPRIATEDexpropriated v. Simple past tense and past participle of expropriate.
EXPROPRIATE v. to deprive of possession or proprietary rights.
EXOPEPTIDASESexopeptidases n. Plural of exopeptidase.
EXOPEPTIDASE n. any of a group of enzymes that hydrolyze peptide bonds.
PERPLEXEDNESSperplexedness n. The quality of being perplexed; bafflement; confusion.
perplexedness n. (Obsolete) The quality of being intricate, complicated or entangled.
PERPLEXEDNESS n. the state of being perplexed.
PERPLEXEDNESSESPERPLEXEDNESS n. the state of being perplexed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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