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There are 20 words containing 2D, H, M, S and T

HIDDENMOSThiddenmost adj. Most deeply hidden.
HIDDENMOST adj. most tucked away, most hidden.
MASTHEADEDmastheaded v. Simple past tense and past participle of masthead.
MASTHEAD v. to raise to the masthead; to punish by sending to the masthead.
METHODISEDmethodised v. Simple past tense and past participle of methodise.
METHODISE v. to reduce to method; to arrange in an orderly way; as, to methodize one's work or thoughts, also METHODIZE.
MISDIGHTEDMISDIGHT v. (Spenser) to mismanage or treat badly.
HANDSTAMPEDhandstamped v. Simple past tense and past participle of handstamp.
HANDSTAMP v. to stamp by hand.
HOMESTEADEDhomesteaded v. Simple past tense and past participle of homestead.
HOMESTEAD v. to acquire a homestead.
DICHOTOMISEDdichotomised v. Simple past tense and past participle of dichotomise.
DICHOTOMISE v. to render dichotomous, also DICHOTOMIZE.
METALDEHYDESMETALDEHYDE n. a polymer of acetaldehyde.
SEMIDETACHEDsemidetached adj. Alternative spelling of semi-detached.
semidetached n. Alternative spelling of semi-detached.
semi-detached adj. Of a house: joined to another one on one side, having one shared wall.
THALIDOMIDESthalidomides n. Plural of thalidomide.
THALIDOMIDE n. a nonbarbiturate sedative drug, withdrawn in 1961 because found to cause malformation in the fetus if taken during pregnancy.
UNMETHODISEDUNMETHODISED adj. not methodised, also UNMETHODIZED.
DIETHYLAMIDESdiethylamides n. Plural of diethylamide.
DIETHYLAMIDE n. as in lysergic acid diethylamide, LSD.
MIDDLEWEIGHTSmiddleweights n. Plural of middleweight.
MIDDLEWEIGHT n. a weight division in boxing.
MITHRIDATISEDmithridatised v. Simple past tense and past participle of mithridatise.
MITHRIDATISE v. to acquire immunity to a poison acquired by taking gradually increased doses of it, also MITHRIDATIZE.
RHODOMONTADESrhodomontades n. Plural of rhodomontade.
RHODOMONTADE v. to boast, rant, also RODOMONTADE.
SEMIDETACHEDSsemidetacheds n. Plural of semidetached.
semi-detacheds n. Plural of semi-detached.
SEMIDETACHED n. one of a pair of residences joined into one building by a common sidewall.
DEMYTHOLOGISEDdemythologised v. Simple past tense and past participle of demythologise.
DEMYTHOLOGISE v. to remove mythology from in order to arrive at the basic meaning, also DEMYTHOLOGIZE.
AZIDOTHYMIDINESazidothymidines n. Plural of azidothymidine.
AZIDOTHYMIDINE n. a derivative of thymidine.
DIMENHYDRINATESdimenhydrinates n. Plural of dimenhydrinate.
DIMENHYDRINATE n. a crystalline antihistamine used esp. to prevent nausea, as in motion sickness.
HYDRODYNAMICISThydrodynamicist n. One who studies hydrodynamics.
HYDRODYNAMICIST n. a student of hydrodynamics.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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