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There are 12 words containing 2D, E, Q and 2U

DEQUEUED	• dequeued v. Simple past tense and past participle of dequeue. • DEQUEUE v. to remove from a (computing) queue.
QUADRUPED	• quadruped n. A four-footed or four-legged animal. • quadruped n. A mammal ambulating on all fours. • QUADRUPED n. a four-footed animal.
QUADRUPEDS	• quadrupeds n. Plural of quadruped. • QUADRUPED n. a four-footed animal.
QUADRUPLED	• quadrupled v. Simple past tense and past participle of quadruple. • QUADRUPLE v. to increase fourfold.
DISQUIETUDE	• disquietude n. (Uncountable) A state of disquiet, uneasiness, or anxiety. • disquietude n. (Countable) A fear or an instance of uneasiness. • DISQUIETUDE n. anxiety, agitation.
QUADRUPEDAL	• quadrupedal adj. Walking on four feet. • QUADRUPEDAL adj. having four feet.
UNDERQUOTED	• underquoted v. Simple past tense and past participle of underquote. • UNDERQUOTE v. to offer at a price lower than.
DISQUIETUDES	• disquietudes n. Plural of disquietude. • DISQUIETUDE n. anxiety, agitation.
QUADRUPLEXED	• quadruplexed adj. Having a quadruplex arrangement. • QUADRUPLEX v. to make quadruplex.
UNLIQUIDATED	• unliquidated adj. (Law) Not liquidated; unascertained. • UNLIQUIDATED adj. not liquidated.
QUADRUPLICATED	• quadruplicated v. Simple past tense and past participle of quadruplicate. • quadruplicated adj. Replicated four times. • QUADRUPLICATE v. to make quadruple or fourfold.
UNDERQUALIFIED	• underqualified adj. Lacking the suitable qualifications for a particular job. • UNDERQUALIFIED adj. insufficiently qualified.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

English Wiktionary: 101 words
Scrabble in French: 12 words
Scrabble in Spanish: 16 words
Scrabble in Italian: 5 words
Scrabble in German: no word
Scrabble in Romanian: no word

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