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There are 20 words containing 2D, E, P, R and Z

DEPAUPERIZEDdepauperized v. Simple past tense and past participle of depauperize.
DEPAUPERIZE v. to free from pauperdom, also DEPAUPERISE.
DEPERSONALIZEDdepersonalized v. Simple past tense and past participle of depersonalize.
DEPERSONALIZE v. to deprive of the sense of personal identity, also DEPERSONALISE.
DEPOLARIZEDdepolarized v. Simple past tense and past participle of depolarize.
DEPOLARIZE v. to remove the polarity from, also DEPOLARISE.
DEPOLYMERIZEDdepolymerized v. Simple past tense and past participle of depolymerize.
DEPOLYMERIZE v. to break a large molecule into simpler ones that have the same basic formula, also DEPOLYMERISE.
DEPRESSURIZEDdepressurized v. Simple past tense and past participle of depressurize.
DEPRESSURIZE v. to reduce the air pressure in esp. suddenly, also DEPRESSURISE.
DESPIRITUALIZEDdespiritualized v. Simple past tense and past participle of despiritualize.
DESPIRITUALIZE v. to deprive of spiritual character or influence, also DESPIRITUALISE.
DESULPHURIZEDdesulphurized v. Simple past tense and past participle of desulphurize.
DESULPHURIZE v. to remove the sulphur from a compound, also DESULFURISE, DESULFURIZE, DESULPHURISE.
DISPAUPERIZEDdispauperized v. Simple past tense and past participle of dispauperize.
DISPAUPERIZE v. to free from pauperdom, also DISPAUPERISE.
DISPRIZEDdisprized v. Simple past tense and past participle of disprize.
disprized adj. Undervalued, disparaged.
DISPRIZE v. to depreciate.
JEOPARDIZEDjeopardized v. Simple past tense and past participle of jeopardize.
JEOPARDIZE v. to expose to loss or injury, also JEOPARDISE.
PEDESTRIANIZEDpedestrianized v. Simple past tense and past participle of pedestrianize.
PEDESTRIANIZE v. to make pedestrian, also PEDESTRIANISE.
PERIODIZEDperiodized v. Simple past tense and past participle of periodize.
PERIODIZE v. to divide into periods, also PERIODISE.
PEROXIDIZEDperoxidized v. Simple past tense and past participle of peroxidize.
PEROXIDIZE v. to oxidize to the utmost degree, so as to form a peroxide, also PEROXIDISE.
PRODIGALIZEDprodigalized v. Simple past tense and past participle of prodigalize.
PRODIGALIZE v. to spend lavishly, to waste, also PRODIGALISE.
PROPAGANDIZEDpropagandized v. Simple past tense and past participle of propagandize.
PROPAGANDIZE v. to subject to propaganda, also PROPAGANDISE.
RHAPSODIZEDrhapsodized v. Simple past tense and past participle of rhapsodize.
RHAPSODIZE v. to utter as a rhapsody, or in the manner of a rhapsody, also RHAPSODISE.
SPHEROIDIZEDspheroidized v. Simple past tense and past participle of spheroidize.
SPHEROIDIZE v. to develop spherulitic or granular structure in, also SPHEROIDISE.
UNDEREMPHASIZEDunderemphasized adj. Insufficiently emphasized.
UNDEREMPHASIZE v. to emphasise insufficiently, also UNDEREMPHASISE.
UNDERPRIZEDunderprized v. Simple past tense and past participle of underprize.
UNDERPRIZE v. to value too little.
UNDERPUBLICIZEDunderpublicized adj. Given inadequate publicity.
UNDERPUBLICIZED adj. insufficiently publicized, also UNDERPUBLICISED.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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