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There are 11 words containing 2D, E, M, S and Z

MIDSIZEDmidsized adj. Of medium size, not particularly large or small.
MIDSIZED adj. medium.
DUMBSIZEDdumbsized v. Simple past tense and past participle of dumbsize.
DUMBSIZE v. to reduce the size of a workforce so low that the work cannot be done effectively.
SODOMIZEDsodomized v. Simple past tense and past participle of sodomize.
SODOMIZE v. to engage in sodomy with, also SODOMISE.
DAMINOZIDESDAMINOZIDE n. a kind of pesticide used on apple trees.
PSALMODIZEDpsalmodized v. Simple past tense and past participle of psalmodize.
PSALMODIZE v. to practice psalmody, also PSALMODISE.
DEDRAMATIZESdedramatizes v. Third-person singular simple present indicative form of dedramatize.
DEDRAMATIZE v. to play down the importance of, lessen or keep low the tension or friction caused by also DEDRAMATISE.
DOMESTICIZEDdomesticized v. Simple past tense and past participle of domesticize.
DOMESTICIZE v. to make domestic, also DOMESTICISE.
DESTIGMATIZEDdestigmatized v. Simple past tense and past participle of destigmatize.
DISHARMONIZEDdisharmonized v. Simple past tense and past participle of disharmonize.
DISHARMONIZE v. to put out of harmony, also DISHARMONISE.
AZIDOTHYMIDINESazidothymidines n. Plural of azidothymidine.
AZIDOTHYMIDINE n. a derivative of thymidine.
UNDEREMPHASIZEDunderemphasized adj. Insufficiently emphasized.
UNDEREMPHASIZE v. to emphasise insufficiently, also UNDEREMPHASISE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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