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There are 10 eight-letter words containing D, M, 2O, S and U

DORMOUSEdormouse n. Any of several species of small, mostly European rodents of the family Gliridae; also called Myoxidae…
dormouse n. Glis glis, the edible dormouse.
dormouse n. (UK) Muscardinus avellanarius, the hazel dormouse.
GUMWOODSgumwoods n. Plural of gumwood.
GUMWOOD n. the wood of a gumtree.
HOODLUMShoodlums n. Plural of hoodlum.
HOODLUM n. a smalltime criminal or gangster.
ISODOMUMisodomum n. Isodomon.
ISODOMUM n. a type of masonry, also ISODOMON.
MODIOLUSmodiolus n. (Anatomy) The central core of the cochlea.
modiolus n. (Anatomy) A chiasma of facial muscles held together by fibrous tissue.
Modiolus prop.n. A taxonomic genus within the family Mytilidae – horsemussel.
MOONDUSTmoondust n. The fine regolith found on the surface of the Moon.
MOONDUST n. dust on the moon.
MUDHOOKSmudhooks n. Plural of mudhook.
MUDHOOK n. (slang) an anchor.
MUDROOMSmudrooms n. Plural of mudroom.
mud␣rooms n. Plural of mud room.
MUDROOM n. a room for shedding muddy clothing.
OUTMODESoutmodes v. Third-person singular simple present indicative form of outmode.
OUTMODE v. to put out of fashion.
QUOMODOSquomodos n. Plural of quomodo.
QUOMODO n. (Latin) a means or manner.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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