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There are 19 eight-letter words containing D, 2I, M, O and S

DIOECISMdioecism n. The devolution of a city into its formerly subordinate constituents, the opposite of synoecism.
dioecism n. (Biology) The condition of being dioecious.
DIOECISM n. the condition of being dioecious, having male and female sexual organs in different individuals.
DIORISMSdiorisms n. Plural of diorism.
DIORISM n. a distinction, a definition.
DISODIUMdisodium n. (Chemistry, in combination) two atoms of sodium in a compound.
DISODIUM adj. of a molecule, having two sodium atoms.
DISOMIESdisomies n. Plural of disomy.
DISOMY n. the state of being disomic, having a number of chromosomes duplicated.
DOMICILSdomicils n. Plural of domicil.
DOMICIL v. to establish in a residence, also DOMICILE.
DOMINIESdominies n. Plural of dominie.
DOMINIE n. a schoolmaster, a tutor.
HOMINIDShominids n. Plural of hominid.
HOMINID n. a manlike creature, also HOMINIAN.
IDIOTISMidiotism n. (Now chiefly historical) Very severe mental retardation.
idiotism n. A foolish utterance.
idiotism n. Idiom.
IDOLISMSidolisms n. Plural of idolism.
IDOLISM n. worship of idols.
IMBODIESimbodies v. Third-person singular simple present indicative form of imbody.
IMBODY v. to form into a body, also EMBODY.
ISTHMOIDisthmoid n. (Graph theory) A set of vertices of a graph after whose deletion the graph is no longer connected.
ISTHMOID adj. pertaining to an isthmus, also ISTHMIC.
MIDIRONSmidirons n. Plural of midiron.
mid-irons n. Plural of mid-iron.
MIDIRON n. a golf club.
MINISODEminisode n. (Informal) A very short episode of a television programme.
MINISODE n. a heavily abridged version of a television episode, esp. as broadcast on the Internet.
MISDOINGmisdoing n. An act of misdoing; a misdeed.
misdoing v. Present participle of misdo.
MISDOING n. the act of doing wrong.
MODIFIESmodifies v. Third-person singular simple present indicative form of modify.
MODIFY v. to alter slightly.
PIGMOIDSpigmoids n. Plural of pigmoid.
PIGMOID n. a pigmy.
PRISMOIDprismoid adj. Resembling a prism.
prismoid n. (Geometry) A prismatoid that has planar sides, and the same number of vertices in both of its parallel planes.
prismoid n. (Geometry) An antiprism.
SIGMOIDSsigmoids n. Plural of sigmoid.
SIGMOID n. an S-shaped curve in a bodily part.
SOLIDISMsolidism n. (Medicine, obsolete) The doctrine that the solid parts of the body are the only parts that have vital…
SOLIDISM n. a doctrine on disease.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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