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There are 13 eight-letter words containing 2D, 3E and F

DEAFENEDdeafened v. Simple past tense and past participle of deafen.
DEAFEN v. to make deaf.
DEFEATEDdefeated adj. Subjugated, beaten, overcome.
defeated v. Simple past tense and past participle of defeat.
DEFEAT v. to win a victory over.
DEFECTEDdefected v. Simple past tense and past participle of defect.
DEFECT v. to desert an allegiance.
DEFENCEDdefenced v. Simple past tense and past participle of defence.
DEFENCE v. to make a defence, also DEFENSE.
DEFENDEDdefended v. Simple past tense and past participle of defend.
DEFEND v. to protect.
DEFENDERdefender n. Someone who defends people or property.
defender n. (Sports) One of the players whose primary task is to prevent the opposition from scoring.
defender n. A fighter who seeks to repel an attack.
DEFENSEDDEFENSE v. to guard against a specific attack, also DEFENCE.
DEFERREDdeferred v. Simple past tense and past participle of defer.
deferred adj. Delayed; put off till later.
deferred adj. Yielded to someone else’s decision or judgment.
DEFLEAEDdefleaed v. Simple past tense and past participle of deflea.
DEFLEA v. to rid of fleas.
DEFLEXEDdeflexed adj. Bent downward, as branches, leaves, or hairs.
DEFLEX v. to bend down.
DEFUELEDdefueled v. Simple past tense and past participle of defuel.
DEFUEL v. to remove fuel from.
FENDEREDfendered adj. Having a specified kind or number of fenders.
FENDERED adj. having a fender.
REDEFIEDredefied v. Simple past tense and past participle of redefy.
REDEFY v. to defy again.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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