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There are 15 fifteen-letter words containing D, E, 2F and 2I

AFFORDABILITIESaffordabilities n. Plural of affordability.
AFFORDABILITY n. the quality of being affordable.
DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DIFFERENTIATINGdifferentiating v. Present participle of differentiate.
DIFFERENTIATE v. to obtain the mathematical derivative of.
DIFFERENTIATIONdifferentiation n. The act or process of differentiating (generally, without a specialized sense).
differentiation n. (Biology) The process by which the components of multicellular life (Cells, organs, etc.) are produced…
differentiation n. (Biology, evolution) The evolutionary process by which one taxonomic group (Species, genus, variety…
DIFFERENTIATORSdifferentiators n. Plural of differentiator.
DIFFERENTIATOR n. someone who or that which differentiates.
DIFFRACTIVENESSDIFFRACTIVE n. causing diffraction.
DIFFRACTOMETRICdiffractometric adj. Relating to diffractometry; measured using a diffractometer.
DIFFRACTOMETRIC adj. relating to measurement by diffractometer, an instrument for determining structure of crystal through light diffraction.
DIFFUSIBILITIESdiffusibilities n. Plural of diffusibility.
DIFFUSIBILITY n. the state of being diffusible.
DIFFUSIVENESSESdiffusivenesses n. Plural of diffusiveness.
DIFFUSIVENESS n. the state of being diffusive.
DISAFFECTIONATEdisaffectionate adj. Not disposed to affection; unfriendly.
DISAFFECTIONATE adj. showing disaffection.
FORISFAMILIATEDforisfamiliated v. Simple past tense and past participle of forisfamiliate.
FORISFAMILIATE v. (Scots) to emancipate from parental authority.
INDIFFERENTISMSindifferentisms n. Plural of indifferentism.
INDIFFERENTISM n. the belief that all religions are equally valid.
INDIFFERENTISTSindifferentists n. Plural of indifferentist.
INDIFFERENTIST n. an exponent of indifferentism.
INTERDIFFUSIONSinterdiffusions n. Plural of interdiffusion.
INTERDIFFUSION n. the process of diffusing and mixing freely so as to approach a homogeneous mixture.
UNDERFULFILLINGUNDERFULFIL v. to fail to fulfil completely, also UNDERFULFILL.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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