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There are 12 fifteen-letter words containing 2D, 2E and 2R

CHORDAMESODERMSCHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DEHYDRORETINOLSDEHYDRORETINOL n. vitamin A2.
DISINCARCERATEDdisincarcerated v. Simple past tense and past participle of disincarcerate.
DISINCARCERATE v. to free from incarceration.
FURFURALDEHYDESFURFURALDEHYDE n. a liquid obtained by heating bran with dilute sulphuric acid, also FURAL, FURFURAL, FURFUROL, FURFUROLE, FUROL, FUROLE.
HARDHEARTEDNESShardheartedness n. (Uncountable) The state of being hardhearted.
hardheartedness n. (Countable) A hardhearted thought or act.
hard-heartedness n. Alternative form of hardheartedness.
SUPERCALENDEREDsupercalendered v. Simple past tense and past participle of supercalender.
SUPERCALENDER v. to give a high polish to.
TENDERHEARTEDLYtenderheartedly adv. In a tenderhearted manner, with caring and compassion.
tender-heartedly adv. Alternative form of tenderheartedly.
TENDERHEARTED adv. easily moved to love, pity, or sorrow.
ULTRACREPIDATEDultracrepidated v. Simple past tense and past participle of ultracrepidate.
ULTRACREPIDATE v. to criticize beyond sphere of one's knowledge.
UNDERDELIVERINGunderdelivering v. Present participle of underdeliver.
UNDERDELIVER v. to fail to achieve what has been expected or promised.
UNDERGRADUETTESundergraduettes n. Plural of undergraduette.
UNDERGRADUETTE n. a female undergraduate.
UNDERPRIVILEGEDunderprivileged adj. Deprived of the opportunities and advantages of others, usually through no fault of one’s own.
underprivileged n. A deprived person; deprived people (normally used as a plural).
UNDERPRIVILEGED adj. deprived through social or economic condition of some of the fundamental rights of all members of a civilized society.
UNDERSUBSCRIBEDundersubscribed adj. Having too few subscribers or subscriptions.
undersubscribed v. Simple past tense and past participle of undersubscribe.
UNDERSUBSCRIBED adj. insufficiently subscribed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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