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There are 12 twelve-letter words containing D, E, M, S, T and X

AMBIDEXTROUSambidextrous adj. Having equal ability in both hands; in particular, able to write equally well with both hands.
ambidextrous adj. Equally usable by left-handed and right-handed people (as a tool or instrument).
ambidextrous adj. (Archaic) Practising or siding with both parties.
DOMINATRIXESdominatrixes n. Plural of dominatrix.
DOMINATRIX n. a prostitute catering for masochists.
EXTEMPORISEDextemporised v. Simple past tense and past participle of extemporise.
EXTEMPORISE v. to perform without preparation or practice; to improvise, also EXTEMPORIZE.
HEXAMETRISEDHEXAMETRISE v. to put into hexameters, also HEXAMETRIZE.
MODERATRIXESmoderatrixes n. Plural of moderatrix.
MODERATRIX n. (obsolete) a female moderator.
MYXEDEMATOUSmyxedematous adj. Relating to, or exhibiting, myxedema.
MYXEDEMATOUS adj. (US) relating to myxedema, a skin disease, also MYXOEDEMATOUS.
OXIDIMETRIESOXIDIMETRY n. a branch of volumetric analysis in which oxidizing agents are used in titrations.
SEXTODECIMOSsextodecimos n. Plural of sextodecimo.
SEXTODECIMO n. a book size 5 5/8 in. x 4 3/8 in. (abbreviated as 16mo.), also SIXTEENMO.
TAXIDERMISEDtaxidermised v. Simple past tense and past participle of taxidermise.
TAXIDERMISE v. to practise taxidermy, also TAXIDERMIZE.
TAXIDERMISESTAXIDERMISE v. to practise taxidermy, also TAXIDERMIZE.
TAXIDERMISTStaxidermists n. Plural of taxidermist.
TAXIDERMIST n. one who practises taxidermy.
TAXIDERMIZEStaxidermizes v. Third-person singular simple present indicative form of taxidermize.
TAXIDERMIZE v. to practise taxidermy, also TAXIDERMISE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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