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There are 17 twelve-letter words containing 2D, M, R, S and U

ARCHDUKEDOMSarchdukedoms n. Plural of archdukedom.
ARCHDUKEDOM n. the domain of an archduke.
DARMSTADTIUMdarmstadtium n. A transuranic chemical element (symbol Ds) with atomic number 110.
DARMSTADTIUM n. an artificially produced radioactive element.
DEFRAUDMENTSdefraudments n. Plural of defraudment.
DEFRAUDMENT n. the act of defrauding.
DEMODULATORSdemodulators n. Plural of demodulator.
DEMODULATOR n. something that demodulates.
DIASCORDIUMSDIASCORDIUM n. (obsolete) a medicine made from water-germander, etc.
DISEMBURDENSdisemburdens v. Third-person singular simple present indicative form of disemburden.
DISEMBURDEN v. to disburden.
DUMBFOUNDERSdumbfounders n. Plural of dumbfounder.
DUMBFOUNDER v. to strike dumb; to confuse with astonishment, also DUMBFOUND, DUMFOUND, DUMFOUNDER.
GOURMANDISEDgourmandised v. Simple past tense and past participle of gourmandise.
GOURMANDISE v. to indulge a taste for good food to excess, also GORMANDISE, GORMANDIZE, GOURMANDIZE.
HYDROMEDUSAEhydromedusae n. Plural of hydromedusa.
HYDROMEDUSA n. a hydrozoan in its medusoid stage, also HYDROMEDUSAN, HYDROMEDUSOID.
HYDROMEDUSANhydromedusan adj. (Zoology) Relating to the hydromedusas.
HYDROMEDUSAN n. a hydromedusa, also HYDROMEDUSA, HYDROMEDUSOID.
HYDROMEDUSAShydromedusas n. Plural of hydromedusa.
HYDROMEDUSA n. a hydrozoan in its medusoid stage, also HYDROMEDUSAN, HYDROMEDUSOID.
MIDDLEBUSTERmiddlebuster n. (US, regional) A type of plough with two mouldboards, which throws earth out to either side.
MIDDLEBUSTER n. a plow with a double moldboard, used to prepare the ground for planting by producing furrows and ridges.
MISPERSUADEDmispersuaded v. Simple past tense and past participle of mispersuade.
MISPERSUADE v. to persuade wrongly.
PSEUDORANDOMpseudorandom adj. Of a sequence of numbers, such that it has all the properties of a random sequence following some probability…
PSEUDORANDOM adj. being or involving entities (as numbers) that are selected by a definite computational process but that satisfy one or more standard tests for statistical randomness.
UNDERDAMPERSunderdampers n. Plural of underdamper.
UNDERDAMPER n. in a type of upright piano, a damper positioned below the hammers.
UNDRAMATISEDundramatised adj. Alternative form of undramatized.
UNDRAMATISED adj. not dramatised, also UNDRAMATIZED.
UNMODERNISEDunmodernised adj. (British spelling) Alternative form of unmodernized.
UNMODERNISED adj. not modernised, also UNMODERNIZED.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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