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There are 17 twelve-letter words containing 2D, 2I, L and P

AMPHIDIPLOIDamphidiploid adj. (Genetics) Having a diploid set of chromosomes from each of its parents.
amphidiploid n. (Biology) Such an organism.
AMPHIDIPLOID n. a hybrid having a complete diploid chromosome set from each parent.
DILAPIDATINGdilapidating v. Present participle of dilapidate.
DILAPIDATE v. to bring into a condition of decay or partial ruin.
DILAPIDATIONdilapidation n. The state of being dilapidated, reduced to decay, partially ruined.
dilapidation n. (Law) The act of dilapidating, damaging a building or structure through neglect or intentionally.
dilapidation n. (Britain, law) Ecclesiastical waste: impairing of church property by an incumbent, through neglect or intentionally.
DILAPIDATORSdilapidators n. Plural of dilapidator.
DILAPIDATOR n. an agent that dilapidates.
DIPLOCARDIACDIPLOCARDIAC adj. of birds and mammals, having a four-chambered heart, which enables two separate circulations and prevents mixing of the arterial and venous blood.
DIPLOMATISEDdiplomatised v. Simple past tense and past participle of diplomatise.
DIPLOMATISE v. to practise, or bring about by, diplomacy, also DIPLOMATIZE.
DIPLOMATIZEDdiplomatized v. Simple past tense and past participle of diplomatize.
DIPLOMATIZE v. to practise, or bring about by, diplomacy, also DIPLOMATISE.
DISPIRITEDLYdispiritedly adv. In a dispirited manner.
DISPIRITED adv. DISPIRIT, to lower in spirits.
DISPLENISHEDdisplenished v. Simple past tense and past participle of displenish.
DISPLENISH v. to deprive or strip, as a house of furniture, or a barn of stock.
DISSIPATEDLYdissipatedly adv. In a dissipated manner.
DISSIPATED adv. DISSIPATE, to scatter or disperse.
HYPODIPLOIDYhypodiploidy n. The state of being hypodiploid; hypoploidy in diploid organisms (including humans).
HYPODIPLOIDY n. the state of being hypodiploid, having slightly fewer than the diploid number of chromosomes.
INDUPLICATEDINDUPLICATED adj. folded inwards, also INDUPLICATE.
PARADIDDLINGparadiddling v. Present participle of paradiddle.
PARADIDDLE v. to make a kind of drum roll using left and right sticks alternately.
PRODIGALISEDprodigalised v. Simple past tense and past participle of prodigalise.
PRODIGALISE v. to spend lavishly, to waste, also PRODIGALIZE.
PRODIGALIZEDprodigalized v. Simple past tense and past participle of prodigalize.
PRODIGALIZE v. to spend lavishly, to waste, also PRODIGALISE.
SIMPLEMINDEDsimpleminded adj. Stupid.
simpleminded adj. Unsophisticated; lacking subtlety.
simple-minded adj. Lacking subtlety or sophistication.
SPLENDIDIOUSsplendidious adj. (Obsolete) splendid.
SPLENDIDIOUS adj. (obsolete) splendid, also SPLENDIDOUS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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