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There are 19 twelve-letter words containing 2D, H, 2O and R

BOROHYDRIDESborohydrides n. Plural of borohydride.
BOROHYDRIDE n. a compound of boron and hydrogen, used as a reducing agent.
CHILDPROOFEDchildproofed v. Simple past tense and past participle of childproof.
CHILDPROOF v. to make an environment safe for a child, or safe from a child.
DAUGHTERHOODdaughterhood n. The condition of being a daughter.
DAUGHTERHOOD n. the state of being a daughter.
DODECAHEDRONdodecahedron n. (Geometry) A polyhedron with twelve faces; the regular dodecahedron has regular pentagons as faces and…
DODECAHEDRON n. (Greek) a twelve-sided solid figure.
ENDOCHONDRALendochondral adj. Within cartilage.
ENDOCHONDRAL adj. relating to a type of ossification affecting cartilage.
FORESHADOWEDforeshadowed v. Simple past tense and past participle of foreshadow.
FORESHADOW v. to represent, indicate, or typify beforehand.
HYDROCODONEShydrocodones n. Plural of hydrocodone.
HYDROCODONE n. a semisynthetic opioid drug derived from codeine and thebaine.
HYDROCOLLOIDhydrocolloid n. Any material that forms a colloid (especially a gel) when mixed with water.
hydrocolloid n. Such a material, made from agar, used to make dental impressions.
HYDROCOLLOID n. a substance that yields a gel with water.
MONOHYDRATEDmonohydrated adj. Hydrated with a single molecule of water.
MONOHYDRATED adj. like a monohydrate.
OVERSHADOWEDovershadowed v. Past participle of overshadow.
overshadowed adj. Superseded by, covered up by, overtaken or eclipsed.
OVERSHADOW v. to cast a shadow over.
PHILODENDRONphilodendron n. Any of several climbing plants, of the genus Philodendron, native to America and the West Indies that…
PHILODENDRON n. any of various aroid plants cultivated for their showy foliage.
PHOTOREDUCEDphotoreduced v. Simple past tense and past participle of photoreduce.
PHOTOREDUCE v. to photocopy with reduction of the image.
PREADULTHOODpreadulthood n. The period of life before adulthood.
RHODODAPHNESRHODODAPHNE n. (Spenser) oleander.
RHODODENDRONrhododendron n. (Obsolete) Oleander (Nerium oleander).
rhododendron n. Any of various flowering shrubs in the genus Rhododendron, especially.
Rhododendron prop.n. A taxonomic genus within the family Ericaceae – rhododendrons and azaleas.
RHODOMONTADErhodomontade n. Dated spelling of rodomontade.
rhodomontade v. Dated spelling of rodomontade.
RHODOMONTADE n. (French) a bragging speech; vain boasting or bluster.
ROADHOLDINGSROADHOLDING n. the qualities of an automobile that tend to make it respond precisely to the driver's steering.
TODDLERHOODStoddlerhoods n. Plural of toddlerhood.
TODDLERHOOD n. the state of being a toddler.
WIDOWERHOODSwidowerhoods n. Plural of widowerhood.
WIDOWERHOOD n. the fact or state of being a widower.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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