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There are 20 twelve-letter words containing 2D, E, H, L and T

ACETALDEHYDEacetaldehyde n. (Organic chemistry) An organic compound, (CH3CHO). Sometimes called ethanal or acetic aldehyde. See…
ACETALDEHYDE n. a chemical compound.
BEETLEHEADEDbeetleheaded adj. Alternative form of beetle-headed.
beetle-headed adj. (Obsolete) Mentally dull; stupid.
BEETLEHEADED adj. like a beetlehead, stupid.
DEMETHYLATEDdemethylated v. Simple past tense and past participle of demethylate.
demethylated adj. (Chemistry) That has been subjected to demethylation.
DEPHLEGMATEDdephlegmated v. Simple past tense and past participle of dephlegmate.
DEPHLEGMATE v. to distill something, such as alcohol.
DIETHYLAMIDEdiethylamide n. (Organic chemistry) The derivative of a compound formed by adding an amide group with two ethyl substituents…
DIETHYLAMIDE n. as in lysergic acid diethylamide, LSD.
ENDOTHELIOIDendothelioid adj. Resembling endothelium.
ENDOTHELIOID adj. of or like the endothelium, the layer of cell tissue on the internal surfaces of blood vessels, lymphatics, etc., also ENDOTHELIAL.
FELDSPATHOIDfeldspathoid n. (Mineralogy) Any of a small group of igneous, plutonic, and volcanic minerals formed in magma that did…
feldspathoid adj. (Mineralogy) Resembling a feldspar.
FELDSPATHOID n. any mineral of a group related to feldspar, also FELSPATHOID, FOID.
FLOODLIGHTEDfloodlighted v. Simple past tense and past participle of floodlight.
floodlighted adj. Lit by floodlights; floodlit.
FLOODLIGHT v. to illuminate by floodlighting.
HYDROXYLATEDhydroxylated v. Simple past tense and past participle of hydroxylate.
hydroxylated adj. (Organic chemistry) That has been modified by hydroxylation.
HYDROXYLATE v. to introduce hydroxyl into.
METALDEHYDESMETALDEHYDE n. a polymer of acetaldehyde.
MIDDLEWEIGHTmiddleweight n. (Uncountable) A weight class in professional boxing between light middleweight or welterweight and super…
middleweight n. (Countable) A boxer who fights in this division; a similar wrestler etc.
middleweight n. (Countable, business, by extension) An employee ranking anywhere between junior and senior.
PREADULTHOODpreadulthood n. The period of life before adulthood.
SADDLECLOTHSsaddlecloths n. Plural of saddlecloth.
saddle-cloths n. Plural of saddle-cloth.
SADDLECLOTH n. a cloth placed under or over a saddle.
SOFTHEADEDLYsoftheadedly adv. In a softheaded manner.
SOFTHEADED adv. having or indicative of a weak, unrealistic, or uncritical mind.
STADTHOLDERSstadtholders n. Plural of stadtholder.
STADTHOLDER n. (Dutch) a Dutch viceroy or provincial governor, also STADHOLDER.
STICKHANDLEDstickhandled v. Simple past tense and past participle of stickhandle.
STICKHANDLE v. to manoeuvre (the puck) deftly in ice hockey.
THALIDOMIDESthalidomides n. Plural of thalidomide.
THALIDOMIDE n. a nonbarbiturate sedative drug, withdrawn in 1961 because found to cause malformation in the fetus if taken during pregnancy.
THUNDERCLOUDthundercloud n. A large, dark cloud, usually a cumulonimbus, charged with electricity and producing thunder and lightning;…
thundercloud n. (By extension, figurative) Something menacing and brooding.
thunder␣cloud n. Alternative spelling of thundercloud.
TODDLERHOODStoddlerhoods n. Plural of toddlerhood.
TODDLERHOOD n. the state of being a toddler.
UNDERCLOTHEDunderclothed v. Simple past tense and past participle of underclothe.
UNDERCLOTHE v. to clothe insufficiently.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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