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There are 20 twelve-letter words containing 2D, 2E, G and L

ACKNOWLEDGEDacknowledged adj. Generally accepted, recognized or admitted.
acknowledged v. Simple past tense and past participle of acknowledg.
acknowledged v. Simple past tense and past participle of acknowledge.
DEGLAMORISEDdeglamorised v. Simple past tense and past participle of deglamorise.
DEGLAMORISE v. to remove the glamour from, also DEGLAMORIZE.
DEGLAMORIZEDdeglamorized v. Simple past tense and past participle of deglamorize.
DEGLAMORIZE v. to remove the glamour from, also DEGLAMORISE.
DEGLUTINATEDdeglutinated v. Simple past tense and past participle of deglutinate.
DEGLUTINATE v. to unglue or unstick.
DEGRINGOLADEdegringolade n. A rapid decline or deterioration; a tumble.
dégringolade n. Alternative spelling of degringolade.
DEGRINGOLADE v. (French) to make a rapid descent.
DENDROLOGIESDENDROLOGY n. the study of trees.
DEPHLEGMATEDdephlegmated v. Simple past tense and past participle of dephlegmate.
DEPHLEGMATE v. to distill something, such as alcohol.
DIGLYCERIDESdiglycerides n. Plural of diglyceride.
DIGLYCERIDE n. an ester formed from glycerol.
DISENTANGLEDdisentangled v. Simple past tense and past participle of disentangle.
DISENTANGLE v. to free from entanglement.
DISLODGEMENTdislodgement n. The state or process of being dislodged.
DISLODGEMENT n. the act of dislodging, also DISLODGMENT.
GIRDLESTEADSgirdlesteads n. Plural of girdlestead.
GIRDLESTEAD n. (obsolete) the waist.
GLASSYHEADEDglassyheaded adj. (Rare) Bald, smooth-headed.
GLASSYHEADED adj. (Tennyson) with a shiny bald head.
GRIDDLEBREADGRIDDLEBREAD n. bread made on a griddle.
GRIDDLECAKESgriddlecakes n. Plural of griddlecake.
griddle␣cakes n. Plural of griddle cake.
GRIDDLECAKE n. a cake made on a griddle.
LOGGERHEADEDloggerheaded adj. Dull; stupid.
LOGGERHEADED adj. like a loggerhead or dunce.
MIDDLEWEIGHTmiddleweight n. (Uncountable) A weight class in professional boxing between light middleweight or welterweight and super…
middleweight n. (Countable) A boxer who fights in this division; a similar wrestler etc.
middleweight n. (Countable, business, by extension) An employee ranking anywhere between junior and senior.
OVERINDULGEDoverindulged v. Simple past tense and past participle of overindulge.
over-indulged v. Simple past tense and past participle of over-indulge.
OVERINDULGE v. to indulge to excess.
SPREADEAGLEDspreadeagled v. Simple past tense and past participle of spreadeagle.
spread-eagled v. Simple past tense and past participle of spread-eagle.
spread-eagled adj. In a spread eagle position.
STRIDELEGGEDstridelegged v. Simple past tense and past participle of strideleg.
stridelegged adj. In a position astride something.
STRIDELEGGED adv. (Scots) astride, also STRIDELEGS.
UNDESIGNEDLYundesignedly adv. In a way that was not designed; as an unexpected consequence; unintentionally.
UNDESIGNED adv. not designed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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