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There are 12 ten-letter words containing 2D, I, 2S and T

DASTARDIESdastardies n. Plural of dastardy.
DASTARDY n. despicable behaviour.
DERMESTIDSdermestids n. Plural of dermestid.
DERMESTID n. any of a family of beetles with clubbed antennae, destructive to organic material.
DISCREDITSdiscredits v. Third-person singular simple present indicative form of discredit.
DISCREDIT v. to refuse to believe in.
DISLUSTREDdislustred v. Simple past tense and past participle of dislustre.
DISLUSTRE v. (archaic) to deprive of lustre.
DISSIDENTSdissidents n. Plural of dissident.
DISSIDENT n. a dissenter, esp. one who disagrees with the aims and procedures of the government.
DISSIPATEDdissipated v. Simple past tense and past participle of dissipate.
dissipated adj. Wasteful of health or possessions in the pursuit of pleasure.
DISSIPATE v. to scatter or disperse.
DISTENDERSdistenders n. Plural of distender.
DISTENDER n. one who distends.
DISTRESSEDdistressed adj. Anxious or uneasy.
distressed adj. (Of merchandise, etc.) damaged.
distressed adj. (Of a property) offered for sale after foreclosure.
DISTRUSTEDdistrusted v. Simple past tense and past participle of distrust.
DISTRUST v. to have no trust in, also MISTRUST.
ESTRILDIDSestrildids n. Plural of estrildid.
ESTRILDID n. any member of a genus of oscinine birds, the weaver-finches.
SHREDDIESTshreddiest adj. Superlative form of shreddy: most shreddy.
SHREDDY adj. cut up.
SUDDENTIESsuddenties n. Plural of suddenty.
SUDDENTY n. (Scots) suddenness.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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