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There are 15 ten-letter words containing 2D, 3I and S

DIMIDIATESdimidiates v. Third-person singular simple present indicative form of dimidiate.
DIMIDIATE v. to divide (a heraldic shield) into halves.
DIMINISHEDdiminished v. Simple past tense and past participle of diminish.
diminished adj. Lessened, reduced.
diminished adj. Made to seem less important, impressive, or valuable.
DIPLOIDIESdiploidies n. Plural of diploidy.
DIPLOIDY n. the condition of being a diploid.
DISDAININGdisdaining v. Present participle of disdain.
disdaining n. Disdain.
DISDAIN v. to scorn, look down on.
DISINVITEDdisinvited v. Simple past tense and past participle of disinvite.
DISINVITE v. to withdraw an invitation to.
DISPIRITEDdispirited v. Simple past tense and past participle of dispirit.
dispirited adj. Without energy, gusto or drive, enervated, without the will to accomplish, disheartened.
DISPIRIT v. to lower in spirits.
EPIDIDYMISepididymis n. (Anatomy) A narrow, tightly-coiled tube connecting the efferent ducts from the rear of each testicle…
EPIDIDYMIS n. a mass of sperm-carrying tubes at the back of the testis.
LIQUIDISEDliquidised v. Simple past tense and past participle of liquidise.
LIQUIDISE v. to make esp. food liquid, also LIQUIDIZE.
MISDIVIDEDmisdivided v. Simple past tense and past participle of misdivide.
MISDIVIDE v. to divide wrongly.
MISDIVIDESmisdivides v. Third-person singular simple present indicative form of misdivide.
MISDIVIDE v. to divide wrongly.
PIDGINISEDpidginised v. Simple past tense and past participle of pidginise.
PIDGINISE v. to make into pidgin, also PIDGINIZE.
QUIDDITIESquiddities n. Plural of quiddity.
QUIDDITY n. the inherent nature of something, also QUIDDIT.
RIGWIDDIESrigwiddies n. Plural of rigwiddie.
rigwiddies n. Plural of rigwiddy.
RIGWIDDIE n. (Scots) a carthorse's backband, also RIGWOODIE.
SOLIDIFIEDsolidified v. Simple past tense and past participle of solidify.
SOLIDIFY v. to make solid.
STIDDIEINGSTIDDIE v. (Old Norse) to forge on an anvil, also STITHY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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