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There are 10 ten-letter words containing 2D, F, 2I and S

DISDAINFULdisdainful adj. Showing contempt or scorn; having a pronounced lack of concern for others viewed as unworthy.
DISDAINFUL adj. full of or expressing disdain, also SDEIGNFULL.
DISFIGUREDdisfigured v. Simple past tense and past participle of disfigure.
DISFIGURE v. to spoil the appearance of.
DISULFIDESdisulfides n. Plural of disulfide.
DISULFIDE n. a sulphide containing two atoms of sulphur to the molecule, also DISULFID, DISULPHIDE, DISULPHURET.
DORSIFIXEDdorsifixed adj. (Botany) Said of anthers that are attached to the filament somewhere along their back.
DORSIFIXED adj. attached at or by the back.
FIDDIOUSEDFIDDIOUS v. (Shakespeare) to treat as leniently as Coriolanus treated Aufidius.
FIDDIOUSESFIDDIOUS v. (Shakespeare) to treat as leniently as Coriolanus treated Aufidius.
MISDEFINEDmisdefined v. Simple past tense and past participle of misdefine.
MISDEFINE v. to define wrongly.
MISFIELDEDmisfielded v. Simple past tense and past participle of misfield.
MISFIELD v. to field badly.
SEMIFREDDIsemifreddi n. Plural of semifreddo.
SEMIFREDDO n. (Italian) a partially frozen Italian dessert similar to ice-cream.
SOLIDIFIEDsolidified v. Simple past tense and past participle of solidify.
SOLIDIFY v. to make solid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 30 words
  • Scrabble in French: no word
  • Scrabble in Spanish: 29 words
  • Scrabble in Italian: 35 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 3 words


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