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There are 18 eight-letter words containing D, 2I, P and U

ASPIDIUMaspidium n. (Dated, countable) Synonym of dryopteris: a genus of ferns or a member of the genus, including the male fern.
aspidium n. (Dated, medicine, uncountable) A vermifuge prepared from the dried male fern.
ASPIDIUM n. (Greek) a type of fern.
BICUSPIDbicuspid adj. Having two points or prominences; ending in two points; said of teeth, leaves, fruit, etc.
bicuspid n. A tooth with two cusps; a premolar tooth.
BICUSPID adj. having two cusps.
CUPIDITYcupidity n. Extreme greed, especially for wealth.
CUPIDITY n. avarice, greed.
DOUPIONIdoupioni n. Alternative form of dupioni.
DOUPIONI n. a kind of silk yarn, also DOUPPIONI, DUPION.
DUPONDIIdupondii n. Plural of dupondius.
DUPONDIUS n. an old Roman coin.
OPHIURIDophiurid adj. Alternative form of ophiuroid.
ophiurid n. Alternative form of ophiuroid.
OPHIURID n. a member of the Ophiura genus of brittle-stars or sand-stars, also OPHIURA, OPHIURAN, OPHIUROID.
PEDICULIpediculi n. Plural of pediculus.
PEDICULUS n. (Latin) any member of the louse genus.
PERIDIUMperidium n. (Mycology) The outer layer that covers the spore-bearing organ in many fungi.
PERIDIUM n. the outer coating of the spore carrier of a fungus.
PRIEDIEUpriedieu n. A kneeling desk for prayers.
prie-dieu n. A piece of furniture on which someone can pray, consisting of a cushioned area to kneel on, with a built-in…
PRIEDIEU n. (French) a low desk with a book-space above and a foot-piece for kneeling in prayer.
PUDICITYpudicity n. Modesty; chastity.
PUDICITY n. modesty; chastity.
PULICIDEpulicide n. Alternative form of pulicicide.
PULICIDE n. an agent used for destroying fleas.
PUNDITICpunditic adj. Of, or related to a pundit.
PUNDITIC adj. like a pundit.
PURIFIEDpurified adj. Made or rendered pure or more pure.
purified v. Simple past tense and past participle of purify.
PURIFY v. to cleanse from impurities.
PYGIDIUMpygidium n. (Zoology) The caudal plate of trilobites, crustacea, and certain insects.
PYGIDIUM n. in trilobites, the posterior division of the body, formed by fusion of the telson with one or more posterior pleurae.
PYXIDIUMpyxidium n. (Botany) A seed capsule in the form of a box, the seeds being released when the top splits off.
PYXIDIUM n. a capsule that opens by a transverse circular split.
TRIPUDIAtripudia n. Plural of tripudium.
TRIPUDIUM n. (Latin) an ancient Roman religious dance in triple time.
UNPITIEDunpitied adj. Not pitied.
UNPITIED adj. not pitied.
UPDIVINGupdiving v. Present participle of updive.
UPDIVE v. to spring upward.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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