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There are 18 fifteen-letter words containing D, E, 2F and N

DEDIFFERENTIATEdedifferentiate v. To lose or reverse differentiation.
DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DEXFENFLURAMINEdexfenfluramine n. A serotonergic anorectic drug used for weight loss in the 1990s, later withdrawn because of cardiovascular…
DIFFERENTIATINGdifferentiating v. Present participle of differentiate.
DIFFERENTIATE v. to obtain the mathematical derivative of.
DIFFERENTIATIONdifferentiation n. The act or process of differentiating (generally, without a specialized sense).
differentiation n. (Biology) The process by which the components of multicellular life (Cells, organs, etc.) are produced…
differentiation n. (Biology, evolution) The evolutionary process by which one taxonomic group (Species, genus, variety…
DIFFERENTIATORSdifferentiators n. Plural of differentiator.
DIFFERENTIATOR n. someone who or that which differentiates.
DIFFERENTNESSESdifferentnesses n. Plural of differentness.
DIFFERENTNESS n. DIFFERENT, separate, unlike.
DIFFRACTIVENESSDIFFRACTIVE n. causing diffraction.
DIFFUSIVENESSESdiffusivenesses n. Plural of diffusiveness.
DIFFUSIVENESS n. the state of being diffusive.
DISAFFECTEDNESSdisaffectedness n. The quality of being disaffected.
DISAFFECTEDNESS n. the state of being disaffected.
DISAFFECTIONATEdisaffectionate adj. Not disposed to affection; unfriendly.
DISAFFECTIONATE adj. showing disaffection.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
INDIFFERENTISMSindifferentisms n. Plural of indifferentism.
INDIFFERENTISM n. the belief that all religions are equally valid.
INDIFFERENTISTSindifferentists n. Plural of indifferentist.
INDIFFERENTIST n. an exponent of indifferentism.
INTERDIFFUSIONSinterdiffusions n. Plural of interdiffusion.
INTERDIFFUSION n. the process of diffusing and mixing freely so as to approach a homogeneous mixture.
OFFHANDEDNESSESOFFHANDEDNESS n. the state of being offhanded.
STANDOFFISHNESSstandoffishness n. The state, quality, or condition of being standoffish or aloof and unsociable; aloofness.
stand-offishness n. Alternative spelling of standoffishness.
STANDOFFISHNESS n. the state of being standoffish.
UNDERFULFILLINGUNDERFULFIL v. to fail to fulfil completely, also UNDERFULFILL.
UNRUFFLEDNESSESUNRUFFLEDNESS n. the state of being unruffled.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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