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There are 20 fifteen-letter words containing D, 2E, F and M

CONFIRMEDNESSESCONFIRMEDNESS n. the state of being confirmed.
COUNTERREFORMEDCOUNTERREFORM v. to make a reform designed to counter another reform.
DEFEMINISATIONSDEFEMINISATION n. the process of defeminising, also DEFEMINIZATION.
DEFEMINIZATIONSdefeminizations n. Plural of defeminization.
DEFEMINIZATION n. the act of defeminizing, also DEFEMINISATION.
DEFORMABILITIESdeformabilities n. Plural of deformability.
DEFORMABILITY n. the quality of being deformable.
DEFRAGMENTATIONdefragmentation n. (Computing) The action of defragmenting, particularly with respect to a computer disk or drive.
DEMOCRATIFIABLEDEMOCRATIFIABLE adj. able to be made democratic.
DEXFENFLURAMINEdexfenfluramine n. A serotonergic anorectic drug used for weight loss in the 1990s, later withdrawn because of cardiovascular…
DIFFRACTOMETERSdiffractometers n. Plural of diffractometer.
DIFFRACTOMETER n. an instrument for determining structure of crystal through light diffraction.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
DISFEATUREMENTSDISFEATUREMENT n. the act of disfeaturing.
FERROMOLYBDENUMferromolybdenum n. An iron-molybdenum alloy.
FERROMOLYBDENUM n. an alloy of iron with molybdenum.
FOREORDAINMENTSforeordainments n. Plural of foreordainment.
FOREORDAINMENT n. the state of being foreordained.
FUNDAMENTALNESSfundamentalness n. The state or condition of being fundamental; essential importance.
FUNDAMENTAL n. basic.
IMMUNODEFICIENTimmunodeficient adj. Exhibiting immunodeficiency.
IMMUNODEFICIENT adj. relating to immunodeficiency, deficiency in immune response due to depletion or inactivity of lymphoid cells.
INDIFFERENTISMSindifferentisms n. Plural of indifferentism.
INDIFFERENTISM n. the belief that all religions are equally valid.
PREMANUFACTUREDpremanufactured v. Simple past tense and past participle of premanufacture.
PREMANUFACTURE v. to manufacture in advance.
UNDERPERFORMERSunderperformers n. Plural of underperformer.
UNDERPERFORMINGunderperforming v. Present participle of underperform.
underperforming adj. That performs less well than required.
UNDERPERFORM v. to perform insufficiently.
UNMINDFULNESSESUNMINDFULNESS n. the state of being unmindful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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