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There are 9 fifteen-letter words containing 2D, E and 2M

CHLAMYDOMONADESCHLAMYDOMONAS n. a member of the genus Chlamydomonas of (mainly freshwater) green algae.
CHORDAMESODERMSCHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DISACCOMMODATEDdisaccommodated v. Simple past tense and past participle of disaccommodate.
DISACCOMMODATE v. to put to inconvenience.
DISACCOMMODATESdisaccommodates v. Third-person singular simple present indicative form of disaccommodate.
DISACCOMMODATE v. to put to inconvenience.
DISCOMMENDATIONdiscommendation n. (Archaic) blame; censure; reproach; shunning.
DISCOMMENDATION n. the act of discommending.
DISCOMMISSIONEDdiscommissioned v. Simple past tense and past participle of discommission.
DISCOMMISSION v. (Milton) to deprive of a commission.
MALADMINISTEREDmaladministered v. Simple past tense and past participle of maladminister.
MALADMINISTER v. to administer wrongly.
MIDDELMANNETJIEmiddelmannetjie n. (South Africa) A ridge between ruts made by wheels in a dirt or gravel road.
MIDDELMANNETJIE n. (South African) a ridge between the ruts made by wheels in a dirt road.
MISCOMPREHENDEDmiscomprehended v. Simple past tense and past participle of miscomprehend.
MISCOMPREHEND v. to comprehend wrongly.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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