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There are 7 twelve-letter words containing 2D, 2P and S

DEPAUPERISEDdepauperised v. Simple past tense and past participle of depauperise.
DEPAUPERISE v. to free from pauperdom, also DEPAUPERIZE.
DIPEPTIDASESdipeptidases n. Plural of dipeptidase.
DIPEPTIDASE n. any of various enzymes that hydrolyze dipeptides but not polypeptides.
DISAPPOINTEDdisappointed adj. Defeated of expectations or hope; experiencing disappointment; let down.
disappointed adj. Expressing or indicating disappointment.
disappointed v. Simple past tense and past participle of disappoint.
EAVESDROPPEDeavesdropped v. Simple past tense and past participle of eavesdrop.
EAVESDROP v. to listen in on a private conversation, also EAVESDRIP.
PREDEPOSITEDpredeposited adj. Deposited in advance.
PREDEPOSIT v. to deposit in advance.
PSEUDOPODIALpseudopodial adj. Of or relating to a pseudopod or to pseudopodia.
PSEUDOPODIAL adj. of or like a pseudopod, also PSEUDOPODAL.
PSEUDOPODIUMpseudopodium n. (Cytology) pseudopod.
PSEUDOPODIUM n. a process protruding from the cell of a protozoan, etc., used for movement or feeding.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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