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There are 6 twelve-letter words containing 2D, E, F and Z

DEFEUDALIZEDdefeudalized v. Simple past tense and past participle of defeudalize.
DEFEUDALIZE v. to deprive of feudal character, also DEFEUDALISE.
DEFEUDALIZESdefeudalizes v. Third-person singular simple present indicative form of defeudalize.
DEFEUDALIZE v. to deprive of feudal character, also DEFEUDALISE.
DEFIBRINIZEDdefibrinized v. Simple past tense and past participle of defibrinize.
DEFIBRINIZE v. to deprive of fibrin, also DEFIBRINISE.
DEFORMALIZEDdeformalized v. Simple past tense and past participle of deformalize.
DEFORMALIZE v. to make less formal, also DEFORMALISE.
DESULFURIZEDdesulfurized v. Simple past tense and past participle of desulfurize.
DESULFURIZE v. to remove the sulphur from a compound, also DESULFURISE, DESULPHURISE, DESULPHURIZE.
UNFEUDALIZEDunfeudalized v. Simple past tense and past participle of unfeudalize.
UNFEUDALIZE v. to deprive of a feudal character, also UNFEUDALISE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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