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There are 15 ten-letter words containing 2D, E and 2M

DEMIMONDESdemimondes n. Plural of demimonde.
demi-mondes n. Plural of demi-monde.
DEMIMONDE n. (French) a class of women on the fringes of respectable society supported by wealthy lovers.
DEMIREPDOMdemirepdom n. The realm or sphere of demireps.
DEMIREPDOM n. the state of being a demirep, a woman of doubtful reputation.
DESMODIUMSdesmodiums n. Plural of desmodium.
DESMODIUM n. a plant of the telegraph-plant genus.
DIAGRAMMEDdiagrammed v. (British spelling) simple past tense and past participle of diagram.
DIAGRAM v. to illustrate by drawing a plan.
DISCOMMENDdiscommend v. (Now rare) To show disapproval of something, find fault with.
discommend v. (Now rare) To speak dissuasively of, to advise against.
DISCOMMEND v. to mention with disapprobation.
DISCOMMODEdiscommode v. (Transitive) To cause inconvenience to (someone).
DISCOMMODE v. to put to inconvenience, also INCOMMODE.
DISIMMUREDDISIMMURE v. to liberate; to release from walls.
DUMMELHEADDUMMELHEAD n. (dialect) a stupid person.
INCOMMODEDincommoded v. Simple past tense and past participle of incommode.
INCOMMODE v. to put to inconvenience, also DISCOMMODE.
MANDAMUSEDmandamused v. Simple past tense and past participle of mandamus.
MANDAMUS v. (Latin) to command by writ from a higher court to a lower.
MEDDLESOMEmeddlesome adj. Characterised or marked by meddling; inclined or having a tendency to meddle or interfere in other people’s…
MEDDLESOME adj. given to meddling.
MIDDLEGAMEmiddlegame n. (Board games) The period in a game between the opening and endgame.
middle␣game n. Alternative form of middlegame.
MIDDLEMOSTmiddlemost adj. Nearest to the exact middle; midmost.
MIDDLEMOST adj. being in the middle, or nearest the middle, also MIDMOST.
MUDDLEMENTmuddlement n. The state of being muddled or the act of muddling; confusion; disorganization.
MUDDLEMENT n. the state of being muddled.
UNBEDIMMEDunbedimmed adj. Not bedimmed.
UNBEDIMMED adj. not made dim.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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