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There are 8 five-letter words containing D, G, R and U

DRUGSdrugs n. Plural of drug.
drugs v. Third-person singular simple present indicative form of drug.
DRUG v. to dose with a medicinal substance.
DURGYdurgy adj. (UK, dialect) Small; undersized.
DURGY adj. dwarfish.
GOURDgourd n. Any of the trailing or climbing vines producing fruit with a hard rind or shell, from the genera Lagenaria…
gourd n. A hard-shelled fruit from a plant in Lagenaria or Cucurbita.
gourd n. The dried and hardened shell of such fruit, made into a drinking vessel, bowl, spoon, or other objects…
GRUEDgrued v. Simple past tense and past participle of grue.
GRUE v. to shudder, feel the flesh creep, also GREW.
GRUNDGRUND adj. as in Scots grund mail, payment for right of burial.
GUARDguard n. A person who, or thing that, protects or watches over something.
guard n. (Ireland) A garda; a police officer.
guard n. (Military) A squad responsible for protecting something.
GURDYgurdy n. (Nautical) A manual crank used on fishing lines.
GURDY n. a winch on a fishing boat.
URGEDurged v. Simple past tense and past participle of urge.
URGE v. to drive forward.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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