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There are 18 twelve-letter words containing D, M, O and X

AMBIDEXTROUSambidextrous adj. Having equal ability in both hands; in particular, able to write equally well with both hands.
ambidextrous adj. Equally usable by left-handed and right-handed people (as a tool or instrument).
ambidextrous adj. (Archaic) Practising or siding with both parties.
APPROXIMATEDapproximated v. Simple past tense and past participle of approximate.
approximated adj. Calculated by approximation.
APPROXIMATE v. to come close to.
COMPLEXIFIEDcomplexified v. Simple past tense and past participle of complexify.
COMPLEXIFY v. to render complex.
COMPLEXIONEDcomplexioned adj. (In combination) Having a specified type of complexion.
COMPLEXIONED adj. having a particular complexion.
DOMINATRIXESdominatrixes n. Plural of dominatrix.
DOMINATRIX n. a prostitute catering for masochists.
EXTEMPORISEDextemporised v. Simple past tense and past participle of extemporise.
EXTEMPORISE v. to perform without preparation or practice; to improvise, also EXTEMPORIZE.
EXTEMPORIZEDextemporized v. Simple past tense and past participle of extemporize.
EXTEMPORIZE v. to perform without preparation or practice; to improvise, also EXTEMPORISE.
HEXAGRAMMOIDHEXAGRAMMOID n. a hexagram shape.
HYDROXONIUMShydroxoniums n. Plural of hydroxonium.
HYDROXONIUM n. the obsolete name for the cation H3O+ derived from protonation of water.
LOXODROMICALloxodromical adj. Synonym of loxodromic.
LOXODROMICAL adj. pertaining to sailing on rhumb lines, also LOXODROMIC.
MALTODEXTRINmaltodextrin n. (Biochemistry) A type of dextrin commonly used as a food additive.
MALTODEXTRIN n. any of various carbohydrates derived from the partial hydrolysis of starch (as of corn or potatoes).
MODERATRIXESmoderatrixes n. Plural of moderatrix.
MODERATRIX n. (obsolete) a female moderator.
MYXEDEMATOUSmyxedematous adj. Relating to, or exhibiting, myxedema.
MYXEDEMATOUS adj. (US) relating to myxedema, a skin disease, also MYXOEDEMATOUS.
OXIDIMETRIESOXIDIMETRY n. a branch of volumetric analysis in which oxidizing agents are used in titrations.
PYRIDOXAMINEpyridoxamine n. (Biochemistry) A constituent of vitamin B6, essential for the metabolism of starch and amino acids.
PYRIDOXAMINE n. a crystalline amine of the vitamin B6 group.
SEXTODECIMOSsextodecimos n. Plural of sextodecimo.
SEXTODECIMO n. a book size 5 5/8 in. x 4 3/8 in. (abbreviated as 16mo.), also SIXTEENMO.
XENODOCHIUMSxenodochiums n. Plural of xenodochium.
XENODOCHIUM n. a building for the reception of strangers, e.g. a guesthouse in a monastery.
XERODERMATICxerodermatic adj. Exhibiting or relating to xeroderma.
XERODERMATIC adj. relating to xeroderma, dryness of skin.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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