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There are 17 four-letter words containing D, E and M

DAMEdame n. (Britain) Usually capitalized as Dame: a title equivalent to Sir for a female knight.
dame n. (Britain) A matron at a school, especially Eton College.
dame n. (Britain, theater) In traditional pantomime: a melodramatic female often played by a man in drag.
DEEMdeem v. (Transitive, obsolete) To judge, to pass judgment on; to doom, to sentence.
deem v. (Transitive, obsolete) To adjudge, to decree.
deem v. (Transitive, obsolete) To dispense (justice); to administer (law).
DEMEdeme n. A township or other subdivision of ancient Attica.
deme n. (Ecology) A distinct local population of plants or animals.
DEME n. (Greek) a territorial subdivision of Attica (also of modern Greece), corresponding to a township.
DEMOdemo n. (Informal) A demonstration or visual explanation.
demo n. (Informal) A recording of a song meant to demonstrate its overall sound for the purpose of getting it…
demo n. (Informal) An example of a product used for demonstration and then sold at a discount.
DEMYdemy n. A printing paper size, 17½ inches by 22½ inches.
demy n. (Colloquial) One holding a demyship, a kind of scholarship for Magdalen College, Oxford.
demy n. Junior scholar, specifically at Magdalen College, Oxford.
DERMderm n. (Anatomy) The integument of animal; the skin.
derm n. Synonym of dermis.
derm n. (Slang) Clipping of dermatologist.
DIMEdime n. (US) A coin worth one-tenth of a U.S. dollar.
dime n. (Canada) A coin worth one-tenth of a Canadian dollar.
dime n. (North America) A small amount of money.
DOMEdome n. (Architecture) A structural element resembling the hollow upper half of a sphere.
dome n. (By extension) Anything shaped like an upset bowl, often used as a cover.
dome n. (Informal) A person’s head.
EMYDemyd n. (Zoology) Any freshwater tortoise of the family Emydidae.
EMYD n. a genus of freshwater terrapin, also EMYDE, EMYS.
IDEMidem pron. The same.
IDEM pron. (Latin) the same; the same as above.
MADEmade n. (UK dialectal or obsolete) A grub or maggot.
made v. Simple past tense and past participle of make.
made v. (Geordie) simple past tense and past participle of myek.
MEADmead n. An alcoholic drink fermented from honey and water.
mead n. (US) A drink composed of syrup of sarsaparilla or other flavouring extract, and water, and sometimes…
mead n. (Poetic) A meadow.
MEDSmeds n. Plural of med.
MEds n. Plural of MEd.
MED n. (short for) medical, medicine.
MEEDmeed n. (Now literary, archaic) A payment or recompense made for services rendered or in recognition of some…
meed n. A gift; bribe.
meed n. (Dated) Merit or desert; worth.
MELDmeld v. (US) to combine multiple similar objects into one.
meld v. In card games, especially of the rummy family, to announce or display a combination of cards.
meld n. A combination of cards which is melded.
MENDmend n. A place, as in clothing, which has been repaired by mending.
mend n. The act of repairing or recovering.
mend v. (Transitive) To repair (something that is torn, broken, defaced, decayed, or otherwise damaged).
MODEmode n. (Music) One of several ancient Greek scales.
mode n. (Music) One of several common scales in modern Western music, one of which corresponds to the modern…
mode n. A particular means of accomplishing something.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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