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There are 14 four-letter words containing D, E and F

DEAFdeaf adj. Unable to hear, or only partially able to hear.
deaf adj. Unwilling to listen or be persuaded; determinedly inattentive; regardless.
deaf adj. Of or relating to the community of deaf people.
DEFIDeFi n. (Finance, cryptocurrencies) Acronym of decentralized finance.
DEFI n. (French) a challenge.
DEFOdefo adj. Alternative form of deffo.
defo adv. Alternative form of deffo.
DEFO interj. definitely, as an expression of agreement or consent.
DEFTdeft adj. Quick and neat in action; skillful.
DEFT adj. skilful.
DEFYdefy v. (Transitive) To challenge (someone) or brave (a hazard or opposition).
defy v. (Transitive) To refuse to obey.
defy v. To not conform to or follow a pattern, set of rules or expectations.
DEIFDEIF adj. (Scots) deaf.
DELFdelf n. A mine, quarry, pit dug; ditch.
delf n. (Heraldry) A charge representing a square sod.
delf n. Alternative form of delft (“style of earthenware”).
FADEfade adj. (Archaic) Weak; insipid; tasteless.
fade n. (Golf) A golf shot that curves intentionally to the player’s right (if they are right-handed) or to…
fade n. A haircut where the hair is short or shaved on the sides of the head and longer on top. See also high-top…
FEDSfeds n. Plural of fed.
feds n. (Slang, government) The federal level of government, viewed as a collective group of people.
FEDs n. Plural of FED.
FEEDfeed v. (Transitive) To give (someone or something) food to eat.
feed v. (Intransitive) To eat (usually of animals).
feed v. (Ditransitive) To give (someone or something) to (someone or something else) as food.
FENDfend v. (Intransitive) To take care of oneself; to take responsibility for one’s own well-being.
fend v. (Rare, except as "fend for oneself") To defend, to take care of (typically construed with for); to block…
fend n. (Obsolete) Self-support; taking care of one’s own well-being.
FEODfeod n. Obsolete form of feud. (estate granted to a vassal by a feudal lord in exchange for service)
FEOD n. a fief or land held on condition of service.
FEUDfeud n. A state of long-standing mutual hostility.
feud n. (Professional wrestling) A staged rivalry between wrestlers.
feud n. (Obsolete) A combination of kindred to avenge injuries or affronts, done or offered to any of their…
FLEDfled v. Simple past tense and past participle of flee.
FLEE v. to run away.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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