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There are 15 words containing 2C, F, I, 2S and U

CIRCUMFUSEScircumfuses v. Third-person singular simple present indicative form of circumfuse.
CIRCUMFUSE v. to pour around or about.
CIRCUMFUSIONScircumfusions n. Plural of circumfusion.
CIRCUMFUSION n. the act of circumfusing, pouring around.
COUCHSURFINGSCOUCHSURFING n. the practice of sleeping overnight in the houses of friends or fellow members of a social network, esp. as an alternative to staying in hotels, hostels, etc.
EFFICACIOUSNESSefficaciousness n. Quality of being efficacious.
EFFICACIOUS n. having the power to produce a desired effect.
FASCICULATIONSfasciculations n. Plural of fasciculation.
FASCICULATION n. muscular twitching involving the simultaneous contraction of contiguous groups of muscle fibers.
FASCICULESfascicules n. Plural of fascicule.
FASCICULE n. a bundle; a division of book published in parts, also FASCICLE, FASCICULUS.
FASCICULUSfasciculus n. (Anatomy) A small bundle of nerve, muscle or tendon fibers.
fasciculus n. One of the divisions of a book published in separate parts; a fascicle.
FASCICULUS n. (Latin) a little bundle; a fascicle, also FASCICLE, FASCICULE.
INSUFFICIENCESINSUFFICIENCE n. the state of being insufficient, also INSUFFICIENCY.
INSUFFICIENCIESinsufficiencies n. Plural of insufficiency.
INSUFFICIENCY n. the state of being insufficient, also INSUFFICIENCE.
SACCHARIFEROUSsacchariferous adj. Producing or containing sugar.
SACCHARIFEROUS adj. bearing sugar.
SUBSPECIFICsubspecific adj. (Taxonomy) pertaining to a subspecies. (See Usage notes.)
subspecific adj. (Taxonomy) infraspecific. (See Usage notes.)
SUBSPECIFIC adj. relating to a subspecies.
SUBSPECIFICALLYsubspecifically adv. (Taxonomy) With regard to a subspecies.
SUBSPECIFIC adv. relating to a subspecies.
SUFFICIENCESsufficiences n. Plural of sufficience.
SUFFICIENCE n. (archaic) a sufficiency.
SUFFICIENCIESsufficiencies n. Plural of sufficiency.
SUFFICIENCY n. the state of being sufficient, also SUFFICIENCE.
UNSELFCONSCIOUSunselfconscious adj. Not self-conscious; natural and genuine.
unself-conscious adj. Alternative spelling of unselfconscious.
UNSELFCONSCIOUS adj. not conscious of oneself.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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