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There are 11 twelve-letter words containing C, 2I, 2O, S and X

DISCONNEXIONdisconnexion n. Dated form of disconnection.
DISCONNEXION n. the act of disconnecting, also DISCONNECTION.
DOXORUBICINSdoxorubicins n. Plural of doxorubicin.
DOXORUBICIN n. a bacterial antibiotic used to treat various forms of cancer.
EXCORIATIONSexcoriations n. Plural of excoriation.
EXCORIATION n. the act of excoriating.
INTOXICATORSintoxicators n. Plural of intoxicator.
INTOXICATOR n. one who intoxicates.
LEXICOLOGIESlexicologies n. Plural of lexicology.
LEXICOLOGY n. the study of words and their meanings.
LEXICOLOGISTlexicologist n. An expert at lexicology.
LEXICOLOGIST n. a practitioner of lexicology.
TOXICOLOGIEStoxicologies n. Plural of toxicology.
TOXICOLOGY n. the science which treats of poisons, their effects, antidotes, and recognition.
TOXICOLOGISTtoxicologist n. A scientist or physician who specializes in toxicology.
TOXICOLOGIST n. an expert in toxicology.
TOXICOMANIAStoxicomanias n. Plural of toxicomania.
TOXICOMANIA n. a morbid craving for poisons.
TOXIPHOBIACSTOXIPHOBIAC n. one who suffers from toxiphobia, fear of poison or being poisoned.
TOXOCARIASIStoxocariasis n. A zoonotic, helminthic infection of humans caused by roundworms of the genus Toxocara.
TOXOCARIASIS n. a disease caused by parasitic worms.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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