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There are 16 twelve-letter words containing C, D, E, G, O and 2S

CLADOGENESEScladogeneses n. Plural of cladogenesis.
CLADOGENESIS n. the evolutionary change and diversification resulting from the branching off of new species from common ancestral lineages.
CLADOGENESIScladogenesis n. (Genetics) An evolutionary splitting event in which each branch and its smaller branches forms a clade.
CLADOGENESIS n. the evolutionary change and diversification resulting from the branching off of new species from common ancestral lineages.
DERECOGNISESderecognises v. Third-person singular simple present indicative form of derecognise.
DERECOGNISE v. to withdraw recognition from (esp. a trade union), also DERECOGNIZE.
DESCHOOLINGSDESCHOOLING n. the freeing of children from the constraints of traditional learning.
DISCOURAGERSdiscouragers n. Plural of discourager.
DISCOURAGER n. one who discourages.
DISENCLOSINGdisenclosing v. Present participle of disenclose.
DISENCLOSE v. to free from being inclosed, also DISINCLOSE.
GALACTOSIDESgalactosides n. Plural of galactoside.
GALACTOSIDE n. a glycoside that yields galactose on hydrolysis.
GIRDLESCONESgirdle␣scones n. Plural of girdle scone.
GIRDLESCONE n. a kind of scone, aka drop scone, also GIRDLECAKE.
GLUCOSIDASESglucosidases n. Plural of glucosidase.
GLUCOSIDASE n. an enzyme, such as maltase, that hydrolyzes a glucoside.
GLYCOSIDASESglycosidases n. Plural of glycosidase.
GLYCOSIDASE n. an enzyme that catalyzes the hydrolysis of a bond joining a sugar of a glycoside to an alcohol or another sugar unit.
GOLDILOCKSESGOLDILOCKS n. a species of buttercup.
SCAFFOLDAGESSCAFFOLDAGE n. the gallery of a theatre, also SCAFFOLAGE.
SCATTERGOODSscattergoods n. Plural of scattergood.
SCATTERGOOD n. a spendthrift.
SOCKDOLAGERSsockdolagers n. Plural of sockdolager.
SOCKDOLAGER n. a conclusive argument, a hard blow, also SLOCKDOLAGER, SLOCKDOLIGER, SLOCKDOLOGER, SOCDOLAGER, SOCDOLIGER, SOCDOLOGER, SOCKDOLIGER, SOCKDOLOGER, SOGDOLAGER, SOGDOLIGER, SOGDOLOGER.
SOCKDOLIGERSSOCKDOLIGER n. a conclusive argument; a hard blow, also SLOCKDOLAGER, SLOCKDOLIGER, SLOCKDOLOGER, SOCDOLAGER, SOCDOLIGER, SOCDOLOGER, SOCKDOLAGER, SOCKDOLOGER, SOGDOLAGER, SOGDOLIGER, SOGDOLOGER.
SOCKDOLOGERSsockdologers n. Plural of sockdologer.
SOCKDOLOGER n. a conclusive argument, a hard blow, also SLOCKDOLAGER, SLOCKDOLIGER, SLOCKDOLOGER, SOCDOLAGER, SOCDOLIGER, SOCDOLOGER, SOCKDOLAGER, SOCKDOLIGER, SOGDOLAGER, SOGDOLIGER, SOGDOLOGER.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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