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There are 7 twelve-letter words containing 2C, 2I, 2M and S

ACADEMICISMSacademicisms n. Plural of academicism.
Academicisms n. Plural of Academicism.
ACADEMICISM n. the doctrine that nothing can be known.
CHEMIOSMOTICchemiosmotic adj. Of or pertaining to chemiosmosis.
CHEMIOSMOTIC adj. relating to a hypothesis to explain ATP formation.
CHROMATICISMchromaticism n. The quality or state of being chromatic.
chromaticism n. The act or action of chromaticizing: the use of chromatic notes or tones (contrasted with diatonicism).
CHROMATICISM n. the state of being chromatic; the use of chromatic tones.
COSMETICISMSCOSMETICISM n. the use of cosmetics.
ECUMENICISMSecumenicisms n. Plural of ecumenicism.
ECUMENICISM n. the doctrines and practice of the Christian ecumenical movement, also ECUMENICALISM.
IMMACULACIESimmaculacies n. Plural of immaculacy.
IMMACULACY n. the state of being immaculate.
MICROSEISMICmicroseismic adj. Describing any small seismic event that causes little or no damage or disturbance.
MICROSEISMIC adj. relating to a microseism, a small earth tremor, also MICROSEISMICAL.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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