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There are 4 ten-letter words containing 2C, 2I, R and 2U

CIRCUITOUScircuitous adj. Not direct or to the point.
circuitous adj. Of a long and winding route.
CIRCUITOUS adj. having a circular or winding course.
CURLICUINGcurlicuing v. Present participle of curlicue.
CURLICUE v. to decorate with fancy spiral figures, also CURLYCUE.
SUBCIRCUITsubcircuit n. A distinct part of an electrical or other circuit.
subcircuit n. (Mathematics) A subset of a circuit.
SUBCIRCUIT n. a part of a circuit.
URICOSURICuricosuric adj. (Medicine) Pertaining to gout suppressants that act directly on the renal tubule to increase the excretion…
uricosuric n. Any medicine of this kind.
URICOSURIC adj. promoting the excretion of uric acid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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