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There are 10 ten-letter words containing 2C, 2I, 2O and S

COLORISTICcoloristic adj. (Art, music) Of, pertaining to, or focused on coloring or an enhanced use of colour.
COLORISTIC adj. relating to a colorist, one who deals with color.
CONCISIONSconcisions n. Plural of concision.
CONCISION n. schism; separation.
CORTICOIDScorticoids n. Plural of corticoid.
CORTICOID n. any of the steroid hormones produced in the adrenal cortex, also CORTICOSTEROID.
CROCOISITEcrocoisite n. Alternative form of crocoite.
CROCOISITE n. a bright red mineral, lead chromate, also CROCOITE.
FINOCCHIOSfinocchios n. Plural of finocchio.
Finocchios prop.n. Plural of Finocchio.
FINOCCHIO n. (Italian) a dwarf variety of fennel, also FINNOCHIO, FINOCHIO.
ISOCALORICisocaloric adj. Having the same calorific value.
isocaloric adj. (Of a diet) Having approximately the same calorific value each day.
ISOCALORIC adj. having similar caloric values.
PICCOLOISTpiccoloist n. One who plays the piccolo.
PICCOLOIST n. one who plays the piccolo.
SCORPIONICScorpionic adj. (Astrology) Of or relating to Scorpio.
SCORPIONIC adj. of or like a scorpion.
SERIOCOMICseriocomic adj. Having both serious and comedic qualities or tendencies.
SERIOCOMIC adj. partly serious and partly comic, also SERIOCOMICAL.
SOCIOLOGICsociologic adj. Of or pertaining to sociology.
SOCIOLOGIC adj. of or relating to sociology, also SOCIOLOGICAL.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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