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There are 15 words containing C, 2E, 2F and M

MALEFFECTmaleffect n. A bad or harmful effect.
MALEFFECT n. an adverse effect.
EFFACEMENTeffacement n. The act of expunging, of wiping out; expungement.
effacement n. Withdrawal in order to make oneself inconspicuous; the making of oneself inconspicuous.
effacement n. (Medicine) A shortening, or thinning, of the cervix before or during early labour.
EFFEMINACYeffeminacy n. The quality of being effeminate.
EFFEMINACY n. the quality of being effeminate.
MALEFFECTSmaleffects n. Plural of maleffect.
MALEFFECT n. an adverse effect.
OFFICEMATEofficemate n. Alternative spelling of office mate.
office␣mate n. One who shares an office with another.
AFFORCEMENTafforcement n. (Obsolete) A reinforcement; a strengthening.
AFFORCEMENT n. the act of afforcing, strengthening a jury by adding skilled people.
COFFEEMAKERcoffeemaker n. (Obsolete) A person who makes coffee.
coffeemaker n. Any of several different types of kitchen apparatus used to brew and filter coffee.
coffee-maker n. Alternative spelling of coffeemaker.
EFFACEMENTSeffacements n. Plural of effacement.
EFFACEMENT n. the act of effacing.
OFFICEMATESofficemates n. Plural of officemate.
office␣mates n. Plural of office mate.
AFFORCEMENTSafforcements n. Plural of afforcement.
AFFORCEMENT n. the act of afforcing, strengthening a jury by adding skilled people.
COFFEEMAKERScoffeemakers n. Plural of coffeemaker.
coffee-makers n. Plural of coffee-maker.
coffee␣makers n. Plural of coffee maker.
EFFEMINACIESeffeminacies n. Plural of effeminacy.
EFFEMINACY n. the quality of being effeminate.
DIFFRACTOMETERdiffractometer n. A device that uses diffraction (especially X-ray diffraction) to investigate the structure of matter.
DIFFRACTOMETER n. an instrument for determining structure of crystal through light diffraction.
AFFRANCHISEMENTaffranchisement n. The act of freeing; enfranchisement.
AFFRANCHISEMENT n. the act of affranchising.
DIFFRACTOMETERSdiffractometers n. Plural of diffractometer.
DIFFRACTOMETER n. an instrument for determining structure of crystal through light diffraction.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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