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There are 8 ten-letter words containing C, 2I, O and 2U

AUSPICIOUSauspicious adj. Of good omen; indicating future success.
auspicious adj. Conducive to success.
auspicious adj. Marked by success; prosperous.
CIRCUITOUScircuitous adj. Not direct or to the point.
circuitous adj. Of a long and winding route.
CIRCUITOUS adj. having a circular or winding course.
CUPIDINOUScupidinous adj. Characterized by or related to cupidity (greed, desire for wealth).
CUPIDINOUS adj. full of desire, amorous.
INCAUTIOUSincautious adj. Careless, reckless, not exercising proper caution.
INCAUTIOUS adj. lacking in caution.
LUBRICIOUSlubricious adj. Smooth and glassy; slippery.
lubricious adj. Lewd, wanton, salacious or lecherous.
LUBRICIOUS adj. slippery; lewd, also LUBRIC, LUBRICAL, LUBRICOUS.
RIDICULOUSridiculous adj. Deserving of ridicule; foolish, absurd.
ridiculous adj. (Informal) astonishing, extreme, unbelievable.
RIDICULOUS adj. arousing or deserving ridicule.
SUSPICIOUSsuspicious adj. Arousing suspicion.
suspicious adj. Distrustful or tending to suspect.
suspicious adj. Expressing suspicion.
URICOSURICuricosuric adj. (Medicine) Pertaining to gout suppressants that act directly on the renal tubule to increase the excretion…
uricosuric n. Any medicine of this kind.
URICOSURIC adj. promoting the excretion of uric acid.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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