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There are 4 eight-letter words containing B, C, 2E, M, R and U

CEREBRUMcerebrum n. (Neuroanatomy) The principal and most anterior part of the brain in vertebrates, which is located in…
CEREBRUM n. (Latin) a part of the brain.
CUMBEREDcumbered adj. (Archaic) Encumbered; hampered.
cumbered v. Simple past tense and past participle of cumber.
CUMBER v. to burden.
CUMBERERcumberer n. Someone or something that cumbers.
CUMBERER n. one who cumbers.
ENCUMBERencumber v. (Transitive) To load down something with a burden.
encumber v. (Transitive) To restrict or block something with a hindrance or impediment.
encumber v. (Transitive) To burden with a legal claim or other obligation.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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