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There are 10 twelve-letter words containing B, F, I, 2R and S

FIBROSARCOMAfibrosarcoma n. (Oncology) A fibroblastic sarcoma: a malignant tumor derived from fibrous connective tissue.
FIBROSARCOMA n. a sarcoma formed of spindle-shaped cells in collagenous fibrils.
FILIBUSTERERfilibusterer n. A person who filibusters.
FILIBUSTERER n. one who filibusters.
FINGERBOARDSfingerboards n. Plural of fingerboard.
FINGERBOARD n. the part of a violin, etc. against which the strings are stopped by the fingers.
MICROFIBRILSmicrofibrils n. Plural of microfibril.
MICROFIBRIL n. a fine fibril.
NEUROFIBRILSneurofibrils n. Plural of neurofibril.
NEUROFIBRIL n. one of a large number of fine fibres present in the cytoplasm of a nerve cell.
REFURBISHERSrefurbishers n. Plural of refurbisher.
REFURBISHER n. one who refurbishes.
REFURBISHINGrefurbishing v. Present participle of refurbish.
refurbishing n. The act by which something is refurbished.
REFURBISHING n. the act of refurbishing.
STROBILIFORMstrobiliform adj. Shaped like a strobile.
STROBILIFORM adj. having the form of a strobil.
SURFBOARDINGsurfboarding v. Present participle of surfboard.
SURFBOARDING n. the sport of surfing on a surfboard.
TUBERIFEROUStuberiferous adj. Producing or bearing tubers.
TUBERIFEROUS adj. bearing tubers.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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