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There are 8 ten-letter words containing B, I, P and 2U

EUPHORBIUMeuphorbium n. An acrid dull yellow or brown resin consisting of the concreted milky juice of several species of Euphorbia…
EUPHORBIUM n. the resinous gum of certain succulent plants of the genus Euphorbia, formerly used as an emetic and purgative.
SUBOPTIMUMsuboptimum adj. Suboptimal.
suboptimum n. A point or value below an optimum.
SUBOPTIMUM n. something that is less than optimal.
SUBSPINOUSsubspinous adj. (Anatomy) subvertebral.
subspinous adj. (Pathology) Situated beneath a spinous process, such as that of the scapula.
SUBSPINOUS adj. subvertebral.
SUPRAPUBICsuprapubic adj. (Anatomy) Above, or anterior to, the pubic bone.
supra-pubic adj. Alternative spelling of suprapubic.
SUPRAPUBIC adj. situated above, or anterior to, the pubic bone.
UNPLUMBINGunplumbing v. Present participle of unplumb.
UNPLUMB v. to remove lead from.
UPBUILDERSUPBUILDER n. one who upbuilds.
UPBUILDINGupbuilding v. Present participle of upbuild.
upbuilding n. The process of building something up; gradual development or accumulation.
UPBUILDING n. development; edification.
UPBURSTINGupbursting n. A bursting upward.
UPBURST v. to burst upwards.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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