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There are 15 fifteen-letter words containing A, F, 2I, O, 2S and U

ANFRACTUOSITIESanfractuosities n. Plural of anfractuosity.
ANFRACTUOSITY n. circuitousness, intricacy.
CONFUSABILITIESCONFUSABILITY n. the quality of being confusable.
DESULFURISATIONDESULFURISATION n. the removal of sulfur or sulfur compounds (as from coal or flue gas), also DESULFURIZATION.
EFFICACIOUSNESSefficaciousness n. Quality of being efficacious.
EFFICACIOUS n. having the power to produce a desired effect.
EMULSIFICATIONSemulsifications n. Plural of emulsification.
EMULSIFICATION n. the act of emulsifying.
FISSIPAROUSNESSfissiparousness n. The quality of being fissiparous.
FISSIPAROUS n. producing new biological units or individuals by fission, as with most strains of bacteria.
FLIRTATIOUSNESSflirtatiousness n. The quality of being flirtatious.
FLIRTATIOUS n. given to flirting.
HYPERFASTIDIOUShyperfastidious adj. Extremely fastidious.
HYPERFASTIDIOUS adj. excessively fastidious.
OMNIFARIOUSNESSomnifariousness n. Quality of being omnifarious.
OMNIFARIOUS n. of all kinds.
SANGUIFICATIONSsanguifications n. Plural of sanguification.
SANGUIFICATION n. blood-making.
STULTIFICATIONSstultifications n. Plural of stultification.
STULTIFICATION n. the act of stultifying.
SUBINFEUDATIONSsubinfeudations n. Plural of subinfeudation.
SUBINFEUDATION n. the sublease of a portion of a feudal estate by a vassal to a tenant who pays fealty to the vassal.
TRANSFUSIONISTStransfusionists n. Plural of transfusionist.
TRANSFUSIONIST n. a doctor who performs transfusions.
ULTRAFASTIDIOUSultrafastidious adj. Extremely fastidious.
ULTRAFASTIDIOUS adj. extremely fastidious.
UNSATISFACTIONSunsatisfactions n. Plural of unsatisfaction.
UNSATISFACTION n. lack of satisfaction.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 63 words
  • Scrabble in French: 54 words
  • Scrabble in Spanish: 34 words
  • Scrabble in Italian: 50 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 12 words


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