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There are 16 twelve-letter words containing A, E, 3I, O and 2S

ANISEIKONIASaniseikonias n. Plural of aniseikonia.
ANISEIKONIA n. a visual condition where image, shape, and size differ in each eye.
ASSOILZIEINGassoilzieing v. Present participle of assoilzie.
ASSOILZIE v. to absolve, to clear a defendant of a charge.
DIAPOSITIVESdiapositives n. Plural of diapositive.
DIAPOSITIVE n. a transparent photographic positive; a slide.
DISSOCIALISEdissocialise v. Alternative form of dissocialize.
DISSOCIALISE v. to make unsocial, also DISSOCIALIZE.
DISSOCIALIZEdissocialize v. (Transitive) To render unsocial.
DISSOCIALIZE v. to make unsocial, also DISSOCIALISE.
DISSOCIATIVEdissociative adj. Removing or separating from some association.
dissociative adj. Causing dissociation.
dissociative adj. (Psychology) related to or caused by dissociation or dissociative disorders.
GRACIOSITIESGRACIOSITY n. graciousness.
HISPANIOLISEHispaniolise v. Alternative form of Hispaniolize.
HISPANIOLISE v. to make Spanish, also HISPANIOLIZE.
INOSILICATESinosilicates n. Plural of inosilicate.
INOSILICATE n. a class of polymeric silicates.
ITEMISATIONSitemisations n. Plural of itemisation.
ITEMISATION n. the act of itemizing, also ITEMIZATION.
MISSIONARIESmissionaries n. Plural of missionary.
MISSIONARY n. a person undertaking a mission and esp. a religious mission.
MISSIONARISEMISSIONARISE v. to do missionary work, also MISSIONARIZE, MISSIONISE, MISSIONIZE.
MISSIONARIZEmissionarize v. Alternative form of missionaryize.
MISSIONARIZE v. to do missionary work, also MISSIONARISE, MISSIONISE, MISSIONIZE.
SEMIOTICIANSsemioticians n. Plural of semiotician.
SEMIOTICIAN n. a practitioner of semiotics, a philosophical theory of signs and symbols, also SEMEIOTICIAN, SEMIOTICIST.
SOLIDARITIESsolidarities n. Plural of solidarity.
SOLIDARITY n. unity (as of a group or class) that produces or is based on community of interests, objectives, and standards.
VARICOSITIESvaricosities n. Plural of varicosity.
VARICOSITY n. the state of being varicose.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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