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There are 18 twelve-letter words containing A, 2E, G, 2I and 2S

ANGIOGENESISangiogenesis n. (Medicine, zoology) The formation and development of new blood vessels.
ANGIOGENESIS n. the development of blood vessels and heart tissue in the embryo.
CAINOGENESIScainogenesis n. Alternative spelling of caenogenesis.
CAINOGENESIS n. the state where adaptations to the needs of the young stages develop early, and disappear in the adult stage.
FRICASSEEINGfricasseeing v. Present participle of fricassee.
FRICASSEE v. to cook as a fricassee.
GAINLINESSESGAINLINESS n. the state of being gainly.
GELATINISERSGELATINISER n. a gelatinising agent, also GELATINIZER.
GLAIRINESSESGLAIRINESS n. the state of being glairy.
GRAININESSESgraininesses n. Plural of graininess.
GRAININESS n. the state of being grainy.
IATROGENESISiatrogenesis n. (Medicine) Any adverse effect (or complication) resulting from medical treatment.
INVESTIGATESinvestigates v. Third-person singular simple present indicative form of investigate.
INVESTIGATE v. to observe or study by close examination and systematic inquiry.
KAINOGENESISKAINOGENESIS n. the state where adaptations to the needs of the young stages develop early, and disappear in the adult stage, also CAENOGENESIS, CENOGENESIS, KENOGENESIS.
LEGISLATIVESlegislatives n. Plural of legislative.
LEGISLATIVE n. the body or department exercising the power and function of legislating.
PALINGENESISpalingenesis n. (Uncountable, also figuratively) Rebirth; regeneration; (countable) an instance of this.
palingenesis n. (Uncountable, biology, chiefly historical or obsolete) The apparent repetition, during the development…
palingenesis n. (Uncountable, geology) The regeneration of magma by the melting of metamorphic rocks.
REGIONALISESregionalises v. Third-person singular simple present indicative form of regionalise.
REGIONALISE v. to divide into regions or administrative districts, also REGIONALIZE.
REGISTRARIESregistraries n. Plural of registrary.
REGISTRARY n. a registrar.
SEIGNIORAGESseigniorages n. Plural of seigniorage.
SEIGNIORAGE n. a government revenue from the manufacture of coins calculated as the difference between the monetary and the bullion value of the silver contained in silver coins.
SERIGRAPHIESserigraphies n. Plural of serigraphy.
SERIGRAPHY n. the making of silkscreen prints.
SKILLIGALEESSKILLIGALEE n. a thin gruel, also SKILLIGOLEE, SKILLY.
TARGETITISESTARGETITIS n. an obsession with achieving targets.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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